LymphedemaV1, Main, Exploration, bibRecord, 002910

Lymphangiogenic factors, mechanisms, and applications

Identifieur interne : 002910 ( Main/Exploration ); précédent : 002909; suivant : 002911

Lymphangiogenic factors, mechanisms, and applications

Auteurs : Wei Zheng ; Aleksanteri Aspelund ; Kari Alitalo [Finlande]

Source :

The Journal of Clinical Investigation [ 0021-9738 ] ; 2014.

RBID : PMC:3934166

Descripteurs français

KwdFr :
- Animaux, Antinéoplasiques (pharmacologie), Humains, Lymphangiogenèse (), Protéines angiogéniques (physiologie), Thérapie moléculaire ciblée, Transduction du signal, Tumeurs (physiopathologie), Tumeurs (traitement médicamenteux), Vaisseaux lymphatiques (physiopathologie).
MESH :
- pharmacologie : Antinéoplasiques.
- physiologie : Protéines angiogéniques.
- physiopathologie : Tumeurs, Vaisseaux lymphatiques.
- traitement médicamenteux : Tumeurs.
- Animaux, Humains, Lymphangiogenèse, Thérapie moléculaire ciblée, Transduction du signal.

English descriptors

KwdEn :
- Angiogenic Proteins (physiology), Animals, Antineoplastic Agents (pharmacology), Humans, Lymphangiogenesis (drug effects), Lymphatic Vessels (physiopathology), Molecular Targeted Therapy, Neoplasms (drug therapy), Neoplasms (physiopathology), Signal Transduction.
MESH :
- chemical , pharmacology : Antineoplastic Agents.
- chemical , physiology : Angiogenic Proteins.
- drug effects : Lymphangiogenesis.
- drug therapy : Neoplasms.
- physiopathology : Lymphatic Vessels, Neoplasms.
- Animals, Humans, Molecular Targeted Therapy, Signal Transduction.

Abstract

Lymphangiogenesis, the growth of lymphatic vessels, is essential in embryonic development. In adults, it is involved in many pathological processes such as lymphedema, inflammatory diseases, and tumor metastasis. Advances during the past decade have dramatically increased the knowledge of the mechanisms of lymphangiogenesis, including the roles of transcription factors, lymphangiogenic growth factors and their receptors, and intercellular and intracellular signaling cascades. Strategies based on these mechanisms are being tested in the treatment of various human diseases such as cancer, lymphedema, and tissue allograft rejection. This Review summarizes the recent progress on lymphangiogenic mechanisms and their applications in disease treatment.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934166

DOI: 10.1172/JCI71603
PubMed: 24590272
PubMed Central: 3934166

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p>Lymphangiogenesis, the growth of lymphatic vessels, is essential in embryonic development. In adults, it is involved in many pathological processes such as lymphedema, inflammatory diseases, and tumor metastasis. Advances during the past decade have dramatically increased the knowledge of the mechanisms of lymphangiogenesis, including the roles of transcription factors, lymphangiogenic growth factors and their receptors, and intercellular and intracellular signaling cascades. Strategies based on these mechanisms are being tested in the treatment of various human diseases such as cancer, lymphedema, and tissue allograft rejection. This Review summarizes the recent progress on lymphangiogenic mechanisms and their applications in disease treatment.</p>
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Serveur d'exploration sur le lymphœdème

Lymphangiogenic factors, mechanisms, and applications

Lymphangiogenic factors, mechanisms, and applications

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
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